Predicting responses to immunotherapy Colon cancers with loss-of-function mutations in the mismatch repair (MMR) pathway have favorable responses to PD-1 blockade immunotherapy....
Biofilms provide refuge for cancerous bacteria Familial adenomatous polyposis (FAP) causes benign polyps along the colon. If left untreated, FAP leads to a high incidence of col...
<p><i>C. difficile</i>–associated tumorigenesis is toxin B (TcdB)–dependent. <b>A,</b> GF <i>Apc<sup>Min/+</sup></i> mice w...
<p><i>C. difficile</i> and the 3728T slurry induce rapid tumorigenesis in GF <i>Apc<sup>Min/+</sup></i> mice despite representing only ...
<p><i>C. difficile</i> induces the activation of myeloid cells and IL17-producing lymphoid subsets. Multiparameter flow cytometry analysis of colonic lamina pr...
Abstract We examined the immune microenvironment of primary colorectal cancer using immunohistochemistry, laser capture microdissection/qRT-PCR, flow cytometry, and functional a...
<p><i>C. difficile</i> strains isolated from human colon cancer mucosa drive colonic tumor formation in GF <i>Apc<sup>Min/+</sup></i> m...
h-index: Number of publications with at least h citations each.