Gregory M. Barton

Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands

A cell biological view of Toll-like receptor function: regulation through compartmentalization

Requirement for Diverse, Low-Abundance Peptides in Positive Selection of T Cells

Whether a single major histocompatibility complex (MHC)–bound peptide can drive the positive selection of large numbers of T cells has been a controversial issue. A diverse popu...

A mechanism for the initiation of allergen-induced T helper type 2 responses

Both metazoan parasites and simple protein allergens induce T helper type 2 (TH2) immune responses, but the mechanisms by which the innate immune system senses these stimuli are...

A calculated response: control of inflammation by the innate immune system

Inflammation is a rapid yet coordinated response that can lead to the destruction of microbes and host tissue. Triggers capable of inducing an inflammatory response include tiss...