Jan A. Staessen

Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials

RISE IN PLASMA CONCENTRATION OF ALDOSTERONE DURING LONG-TERM ANGIOTENSIN II SUPPRESSION

The plasma concentration of aldosterone was followed in seven hypertensive patients before and during long-term angiotensin II suppression with the orally active angiotensin-I-c...

Treatment of hypertension in patients 80 years and older: the lower the better? A meta-analysis of randomized controlled trials

Treating hypertension in very old patients reduces stroke and heart failure with no effect on total mortality. The most reasonable strategy is the one associated with significan...

Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial

Treatment of Hypertension in Patients 80 Years of Age or Older

The results provide evidence that antihypertensive treatment with indapamide (sustained release), with or without perindopril, in persons 80 years of age or older is beneficial....

Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension

Prevalence of Left Ventricular Diastolic Dysfunction in a General Population

Background— Because the process of myocardial remodelling starts before the onset of symptoms, recent heart failure (HF) guidelines place special emphasis on the detection of su...