Luke A. McNeill

Insulated Molecular Wires: Synthesis of Conjugated Polyrotaxanes by Suzuki Coupling in Water

Poly-para-phenylene polyrotaxane 1 is the first conjugated polyrotaxane. The naphthalene end groups prevent the β-cyclodextrin rings from slipping off the conjugated backbone in...

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Variants in the FTO (fat mass and obesity associated) gene are associated with increased body mass index in humans. Here, we show by bioinformatics analysis that FTO shares sequ...

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Highly parallel direct RNA sequencing on an array of nanopores