Michael Bittner

Expression of bacterial genes in plant cells.

Chimeric bacterial genes conferring resistance to aminoglycoside antibiotics have been inserted into the Agrobacterium tumefaciens tumor-inducing (Ti) plasmid and introduced int...

Use of a cDNA microarray to analyse gene expression patterns in human cancer

Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays.

Several forms of human sarcoma, lymphoma, and leukemia are characterized by somatically acquired chromosome translocations that result in fusion genes that encode chimeric trans...

Gene-Expression Profiles in Hereditary Breast Cancer

Significantly different groups of genes are expressed by breast cancers with BRCA1 mutations and breast cancers with BRCA2 mutations. Our results suggest that a heritable mutati...

Direct identification of sickle cell anemia by blot hybridization.

Several reports have been published on the use of polymorphisms found in the human hemoglobin genes as a means for prenatal diagnosis of sickle cell anemia. The disadvantages of...

Electrophoretic transfer of proteins and nucleic acids from slab gels to diazobenzylozymethyl cellulose or nitrocellulose sheets