Salvador Moncada

Indomethacin and Aspirin abolish Prostaglandin Release from the Spleen

Vascular endothelial cells synthesize nitric oxide from L-arginine

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

A soluble enzyme obtained from rat forebrain catalyzes the NADPH-dependent formation of nitric oxide (NO) and citrulline from L-arginine. The NO formed stimulates the soluble gu...

The L-Arginine-Nitric Oxide Pathway

The discovery that mammalian cells generate nitric oxide, a gas previously considered to be merely an atmospheric pollutant, is providing important information about many biolog...

The 1991 Ulf von Euler Lecture:The<scp>l</scp>‐arginine: nitric oxide pathway

‘We must always guard the liberties of the mind and remember that some degree of heresy is often a sign of health in spiritual life.’ U. S. von Euler, Circulation , 26 (1962), 1...

Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension

Objective: There is indirect evidence that the nitric oxide system may be impaired in hypertensive patients. The objective of this study was to examine basal nitric oxide-mediat...

Synthesis of nitric oxide from <scp>l</scp>-arginine by neutrophils. Release and interaction with superoxide anion

Stimulated rat peritoneal neutrophils release a platelet inhibitory factor with the pharmacological properties of NO. This release is inhibited by NG-monomethyl-L-arginine and L...