Wendy Winckler

The Genotype-Tissue Expression (GTEx) project.

Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

Expression, genetic variation, and tissues Human genomes show extensive genetic variation across individuals, but we have only just started documenting the effects of this varia...

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Absolute quantification of somatic DNA alterations in human cancer

Comprehensive molecular portraits of human breast tumours

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Integrated genomic characterization of endometrial carcinoma

Guidelines for investigating causality of sequence variants in human disease

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Integrative genomics viewer

The landscape of somatic copy-number alteration across human cancers

Melanoma genome sequencing reveals frequent PREX2 mutations

Punctuated Evolution of Prostate Cancer Genomes

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

The mutational profile of head and neck cancer is complex and may pose challenges to the development of targeted therapies.

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

High-throughput oncogene mutation profiling in human cancer

Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma

Abstract The classification of human tumors based on molecular criteria offers tremendous clinical potential; however, discerning critical and “druggable” effectors on a large s...

Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions

Somatic genetic alterations in cancers have been linked with response to targeted therapeutics by creation of specific dependency on activated oncogenic signaling pathways. Howe...