Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
Tumor HPV status is a strong and independent prognostic factor for survival among patients with oropharyngeal cancer. (ClinicalTrials.gov number, NCT00047008.)
Publications
6 shownImproved Survival of Patients With Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma in a Prospective Clinical Trial
For patients with HNSCC of the oropharynx, tumor HPV status is strongly associated with therapeutic response and survival.
Distinct Risk Factor Profiles for Human Papillomavirus Type 16–Positive and Human Papillomavirus Type 16–Negative Head and Neck Cancers
HPV-16-positive HNSCCs and HPV-16-negative HNSCCs have different risk factor profiles, indicating that they should be considered to be distinct cancers.
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma.
The tumor suppressor gene p16 (CDKN2/MTS-1/INK4A) can be inactivated by multiple genetic mechanisms. We analyzed 29 invasive primary head and neck squamous cell carcinomas (HNSC...
Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor origin.
For patients with metastatic HNSCC, detection of HPV-16 is a reliable way to establish origin from the oropharynx, either directly by ISH or indirectly by immunohistochemistry f...
Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive<i>p53</i>Gene Mutations in Squamous Cell Carcinoma of the Head and Neck
Abstract Purpose: Squamous cell carcinomas of the head and neck (HNSCC) often harbor p53 mutations, but p53 protein degradation by the viral oncoprotein E6 may supercede p53 mut...
Frequent Co-Authors
Researcher Info
- h-index
- 6
- Publications
- 6
- Citations
- 11,689
- Institution
- Johns Hopkins University
External Links
Impact Metrics
h-index
6
h-index: Number of publications with at least h citations each.