Centre for Genomic Regulation

The Genotype-Tissue Expression (GTEx) project.

Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...

GENCODE: The reference human genome annotation for The ENCODE Project

The GENCODE Consortium aims to identify all gene features in the human genome using a combination of computational analysis, manual annotation, and experimental validation. Sinc...

Transcriptome and genome sequencing uncovers functional variation in humans

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

Whole-genome sequencing of multiple Arabidopsis thaliana populations

The plant Arabidopsis thaliana occurs naturally in many different habitats throughout Eurasia. As a foundation for identifying genetic variation contributing to adaptation to di...

Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer

Standardized benchmarking in the quest for orthologs

Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and functional genomic analyses, yet the true evolutionary history of genes is gen...

Strand-specific deep sequencing of the transcriptome

Several studies support that antisense-mediated regulation may affect a large proportion of genes. Using the Illumina next-generation sequencing platform, we developed DSSS ( d ...