Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

Signatures of mutational processes in human cancer

Hepatocellular carcinoma

Hepatocellular carcinoma (HCC), one of the most frequent tumors in the world, is included by the World Health Organization as a relevant public health problem in areas of high i...

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

BCLC strategy for prognosis prediction and treatment recommendation: The 2022 update

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

Abstract During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD) considering the disease as a continuum. Thanks to evolving biomarker resear...

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance

Abstract Several concepts, which in the aggregate get might be used to account for “resilience” against age‐ and disease‐related changes, have been the subject of much research....

Adult haemophagocytic syndrome

Current Strategy for Staging and Treatment: The BCLC Update and Future Prospects

Staging and treatment indication are relevant topics in the management of patients with hepatocellular carcinoma (HCC) and for optimal results, they have to take into account li...

Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: Prospective validation of the noninvasive diagnostic criteria for hepatocellular carcinoma

This study prospectively evaluates the accuracy of contrast-enhanced ultrasound (CEUS) and dynamic magnetic resonance imaging (MRI) for the diagnosis of nodules 20 mm or smaller...