Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Luke Jostins , Stephan Ripke , Rinse K. Weersma , Luke Jostins , Stephan Ripke , Rinse K. Weersma , Richard H. Duerr , Dermot McGovern , Ken Hui , James Lee , L. Philip Schumm , Yashoda Sharma , Carl A. Anderson , Jonah Essers , Mitja Mitrovič , Kaida Ning , Isabelle Cleynen , Emilie Théâtre , Sarah L. Spain , Soumya Raychaudhuri , Philippe Goyette , Zhi Wei , Clara Abraham , Jean–Paul Achkar , Tariq Ahmad , Leila Amininejad , Ashwin N. Ananthakrishnan , Vibeke Andersen , Jane M. Andrews , Leonard Baidoo , Tobias Balschun , Peter A. Bampton , Alain Bitton , Gabrielle Boucher , Stephan Brand , Carsten Büning , Ariella Cohain , Sven Cichon , Mauro D’Amato , Dirk de Jong , Kathy L. Devaney , Marla C. Dubinsky , Cathryn Edwards , David Ellinghaus , Lynnette Ferguson , Denis Franchimont , Karin Fransén , Richard B. Gearry , Michel Georges , Christian Gieger , Jürgen Glas , Talin Haritunians , Ailsa Hart , Chris Hawkey , Matija Hedl , Xinli Hu , Tom H. Karlsen , Limas Kupčinskas , Subra Kugathasan , Anna Latiano , Debby Laukens , Ian C. Lawrance , Charlie W. Lees , Édouard Louis , Gillian Mahy , John Mansfield , Ann W. Morgan , Craig Mowat , William G. Newman , Orazio Palmieri , Cyriel Y. Ponsioen , Uroš Potočnik , Natalie J. Prescott , Miguel Regueiro , Jerome I. Rotter , Richard K. Russell , Jeremy Sanderson , Miquel Sans , Jack Satsangi , Stefan Schreiber , Lisa A. Simms , Jurgita Šventoraitytė , Stephan R. Targan , Kent D. Taylor , Mark Tremelling , Hein W. Verspaget , Paul Martin , Cisca Wijmenga , David C. Wilson , Juliane Winkelmann , Ramnik J. Xavier , Sebastian Zeißig , Bin Zhang , Hu Zhang , Hongyu Zhao , Mark S. Silverberg , Vito Annese , Hákon Hákonarson , Steven R. Brant , Graham Radford‐Smith , Christopher G. Mathew , John D. Rioux , Eric E. Schadt
2012 Nature 4,728 citations

Keywords

Inflammatory bowel diseaseHost (biology)DiseaseInflammatory Bowel DiseasesGenetic architectureBiologyMedicineGeneticsPathologyGenePhenotype

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Publication Info

Year
2012
Type
review
Volume
491
Issue
7422
Pages
119-124
Citations
4728
Access
Closed

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Luke Jostins, Stephan Ripke, Rinse K. Weersma et al. (2012). Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature , 491 (7422) , 119-124. https://doi.org/10.1038/nature11582

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DOI
10.1038/nature11582