Institut de Neurobiologie de la Méditerranée

Excitatory actions of gaba during development: the nature of the nurture

In the immature brain, GABA (gamma-aminobutyric acid) is excitatory, and GABA-releasing synapses are formed before glutamatergic contacts in a wide range of species and structur...

Dynamic Statistical Parametric Mapping

GABA: A Pioneer Transmitter That Excites Immature Neurons and Generates Primitive Oscillations

Developing networks follow common rules to shift from silent cells to coactive networks that operate via thousands of synapses. This review deals with some of these rules and in...

Trophic actions of GABA on neuronal development

During brain development, transmitter-gated receptors are operative before synapse formation, suggesting that their action is not restricted to synaptic transmission. GABA, whic...

Timing of the Developmental Switch in GABA_A Mediated Signaling from Excitation to Inhibition in CA3 Rat Hippocampus Using Gramicidin Perforated Patch and Extracellular Recordings

Summary: The timing of the developmental switch in the GABA A mediated responses from excitatory to inhibitory was studied in Wistar rat CA3 hippocampal pyramidal cells using gr...

Exploring Microbial Diversity Using 16S rRNA High-Throughput Methods

As a result of advancements in high-throughput technology, the sequencing of the pioneering 16S rRNA gene marker is gradually shedding light on the taxonomic characterization of...

Functional KCC2 expression marks an evolutionarily conserved population of early-maturing interneurons in the perinatal cortex

The developmental shift from depolarizing to hyperpolarizing GABA responses is a pivotal step in the maturation of GABAergic transmission and cortical circuits; classically docu...