Publications
View AllCirculating microRNAs as stable blood-based markers for cancer detection
Improved approaches for the detection of common epithelial malignancies are urgently needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) ...
The Immune Landscape of Cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we identi...
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors ac...
RepeatModeler2 for automated genomic discovery of transposable element families
The accelerating pace of genome sequencing throughout the tree of life is driving the need for improved unsupervised annotation of genome components such as transposable element...
Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner
We define a “threaded blockset,” which is a novel generalization of the classic notion of a multiple alignment. A new computer program called TBA (for “threaded blockset aligner...
Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing
Runs in the Family The power to detect mutations involved in disease by genome sequencing is enhanced when combined with the ability to discover specific mutations that may have...
Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency
Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily share an intracytoplasmic Toll–IL-1 receptor (TIR) domain, which mediates recruitment of t...
Affiliated Researchers
Institution Info
- Type
- nonprofit
- Country
- US
- Publications
- 14
- Citations
- 58,094
External Links
Identifiers
- ROR
- https://ror.org/02tpgw303