Institute of Molecular and Cell Biology

Primer3—new capabilities and interfaces

Polymerase chain reaction (PCR) is a basic molecular biology technique with a multiplicity of uses, including deoxyribonucleic acid cloning and sequencing, functional analysis o...

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Abstract Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These f...

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

Moving beyond P values: data analysis with estimation graphics

New Technologies for Analysis of Extracellular Vesicles

Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by cells. Similar-sized vesicles can be further classified (e.g., exosomes, microvesicles...

Early events in cell adhesion and polarity during epithelial-mesenchymal transition

During evolution from primitive species, a mechanism, termed epithelial-mesenchymal transition (EMT), was established to create mesenchymal cells from a pre-existing epithelial ...

Probiotic metabolites as epigenetic targets in the prevention of colon cancer

Dietary interventions for preventing colon cancer have recently attracted increased attention from researchers and clinicians. The probiotics have emerged as potential therapeut...

Conserved linkage between the puffer fish (Fugu rubripes) and human genes for platelet-derived growth factor receptor and macrophage colony-stimulating factor receptor.

We have cloned and sequenced the teleost homologs of the human genes encoding platelet-derived growth factor receptor-beta (PDGFR beta) and macrophage colony-stimulating factor ...

Targeted therapies in control of EMT in carcinoma and fibrosis