University of Massachusetts Chan Medical School

Full-length transcriptome assembly from RNA-Seq data without a reference genome

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Chromosomal Mapping The conformation of the genome in the nucleus and contacts between both proximal and distal loci influence gene expression. In order to map genomic contacts,...

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

Abstract Objective The 1987 American College of Rheumatology (ACR; formerly, the American Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have been...

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemic...

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCO...

What low back pain is and why we need to pay attention

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

RNAi