CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection

Jason V. Baker; Grace Peng; Joshua Rapkin; Donald I. Abrams; Michael J. Silverberg; Rodger D. MacArthur; Winston Cavert; W. Keith Henry; James D. Neaton

doi:10.1097/qad.0b013e3282f7cb76

Abstract

Higher CD4+ counts on antiretroviral therapy are associated with lower rates of non-AIDS diseases and AIDS. These findings expand our understanding of the implications of HIV-related immunodeficiency and motivate randomized studies to evaluate the effects of antiretroviral therapy on a broad set of clinical outcomes at CD4+ counts greater than 350 cells/microl.

Keywords

MedicineHazard ratioConfidence intervalInternal medicineProportional hazards modelCohortCohort studySidaImmunologyViral diseaseHuman immunodeficiency virus (HIV)

MeSH Terms

Acquired Immunodeficiency SyndromeAdultAnti-HIV AgentsAntiretroviral TherapyHighly ActiveCD4 Lymphocyte CountCardiovascular DiseasesChronic DiseaseFemaleFollow-Up StudiesHIV-1HumansImmune ToleranceKidney DiseasesLiver DiseasesMaleNeoplasmsProportional Hazards ModelsRiskViral Load

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Publication Info

Year: 2008
Type: article
Volume: 22
Issue: 7
Pages: 841-848
Citations: 361
Access: Closed

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APA Style

                            
                                
                                    Jason V. Baker, 
                                
                                    Grace Peng, 
                                
                                    Joshua Rapkin
                                
                                et al.
                            
                            (2008). 
                            CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection. 
                            AIDS
                            , 22
                            (7)
                            , 841-848.
                            https://doi.org/10.1097/qad.0b013e3282f7cb76
                        

Identifiers

DOI: 10.1097/qad.0b013e3282f7cb76
PMID: 18427202
PMCID: PMC3618460

Data Quality

Data completeness: 90%