Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate

for the Chronic Kidney Disease Prognosis Consortium; Kunihiro Matsushita; Bakhtawar K. Mahmoodi; Mark Woodward; Jonathan Emberson; Tazeen H. Jafar; Sun Ha Jee; Kevan R. Polkinghorne; Anoop Shankar; David H. Smith; Marcello Tonelli; David G. Warnock; Chi-Pang Wen; Josef Coresh; Ron T. Gansevoort; Brenda R. Hemmelgarn; Andrew S. Levey

doi:10.1001/jama.2012.3954

Abstract

The CKD-EPI equation classified fewer individuals as having CKD and more accurately categorized the risk for mortality and ESRD than did the MDRD Study equation across a broad range of populations.

Keywords

MedicineRenal functionInterquartile rangeKidney diseasePopulationEpidemiologyEstimating equationsCohortInternal medicineDemographyDiseaseUrologyStatisticsEnvironmental health

Affiliated Institutions

Related Publications

Modified Glomerular Filtration Rate Estimating Equation for Chinese Patients with Chronic Kidney Disease

Yingchun Ma , Li Zuo , Jianghua Chen +10 more

The Modification of Diet in Renal Disease (MDRD) equations provide a rapid method of assessing GFR in patients with chronic kidney disease (CKD). However, previous research indi...

2006 Journal of the American Society of Ne... 1885 citations

Using Serum Creatinine To Estimate Glomerular Filtration Rate: Accuracy in Good Health and in Chronic Kidney Disease

Andrew D. Rule , Timothy S. Larson , Erik J. Bergstralh +3 more

The MDRD equation systematically underestimates GFR in healthy persons. A new equation developed with patients who have chronic kidney disease and healthy persons may be a step ...

2004 Annals of Internal Medicine 1056 citations

Association between Monocyte Count and Risk of Incident CKD and Progression to ESRD

Benjamin Bowe , Yan Xie , Hong Xian +2 more

Background and objectives Experimental evidence suggests a role for monocytes in the biology of kidney disease progression; however, whether monocyte count is associated with ri...

2017 Clinical Journal of the American Soci... 69 citations

Evaluation of the Modification of Diet in Renal Disease Study Equation in a Large Diverse Population

Lesley A. Stevens , Josef Coresh , Harold I. Feldman +8 more

Glomerular filtration rate (GFR) estimates facilitate detection of chronic kidney disease. Performance of the Modification of Diet in Renal Disease (MDRD) Study equation varies ...

2007 Journal of the American Society of Ne... 566 citations

Recommendations for Improving Serum Creatinine Measurement: A Report from the Laboratory Working Group of the National Kidney Disease Education Program

Gary L. Myers , W. Greg Miller , Josef Coresh +8 more

The current variability in serum creatinine measurements renders all estimating equations for GFR, including the MDRD Study equation, less accurate in the normal and slightly in...

2005 Clinical Chemistry 1220 citations

Publication Info

Year: 2012
Type: review
Volume: 307
Issue: 18
Pages: 1941-51
Citations: 969
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

969

OpenAlex

Cite This

APA Style

                            
                                
                                    for the Chronic Kidney Disease Prognosis Consortium, 
                                
                                    Kunihiro Matsushita, 
                                
                                    Bakhtawar K. Mahmoodi
                                
                                et al.
                            
                            (2012). 
                            Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate. 
                            JAMA
                            , 307
                            (18)
                            , 1941-51.
                            https://doi.org/10.1001/jama.2012.3954
                        

Identifiers

DOI: 10.1001/jama.2012.3954