Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

Keywords

BiologyCytotoxic T cellCD8Immune systemPopulationT-cell receptorTumor microenvironmentCancer researchImmunologyT cellImmunotherapyMelanomaCell biologyGeneticsIn vitroMedicine

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Publication Info

Year: 2018
Type: article
Volume: 176
Issue: 4
Pages: 775-789.e18
Citations: 1087
Access: Closed

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APA Style

                            
                                
                                    Hanjie Li, 
                                
                                    Anne M. van der Leun, 
                                
                                    Ido Yofe
                                
                                et al.
                            
                            (2018). 
                            Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma. 
                            Cell
                            , 176
                            (4)
                            , 775-789.e18.
                            https://doi.org/10.1016/j.cell.2018.11.043
                        

Identifiers

DOI: 10.1016/j.cell.2018.11.043

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

Keywords

Affiliated Institutions

Related Publications

VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

Tumor Rejection After Direct Costimulation of CD8 <sup>+</sup> T Cells by B7-Transfected Melanoma Cells

Immune Cell–Poor Melanomas Benefit from PD-1 Blockade after Targeted Type I IFN Activation

Up-Regulation of PD-L1, IDO, and T <sub>regs</sub> in the Melanoma Tumor Microenvironment Is Driven by CD8 <sup>+</sup> T Cells

Publication Info

External Links

Social Impact

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