Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

Erik Volz; Verity Hill; John T. McCrone; Anna Price; David Jorgensen; Áine O’Toole; Joel Southgate; Robert A. Johnson; Ben Jackson; Fabrícia F. Nascimento; Sara Rey; Samuel M. Nicholls; Rachel Colquhoun; Ana da Silva Filipe; James G. Shepherd; David J. Pascall; Rajiv Shah; Natasha Jesudason; Kathy Li; Ruth F. Jarrett; Nicole Pacchiarini; Matthew Bull; Lily Geidelberg; Igor Siveroni; Ian Goodfellow; Nicholas J. Loman; Oliver G. Pybus; David L. Robertson; Emma C. Thomson; Andrew Rambaut; Thomas R. Connor; Cherian Koshy; Emma L. Wise; Nick Cortes; Jessica Lynch; Stephen P. Kidd; Matilde Mori; Derek Fairley; Tanya Curran; James McKenna; Helen Adams; Christophe Fraser; Tanya Golubchik; David Bonsall; Catrin E. Moore; Sarah Caddy; Fahad Khokhar; Michelle Wantoch; Nicola Reynolds; Ben Warne; Joshua Maksimovic; Karla Spellman; Kathryn McCluggage; John P.T. Mo; Robert Beer; Safiah Afifi; Siân Morgan; Angela Marchbank; Anna Price; Christine Kitchen; Huw Gulliver; Ian Merrick; Joel Southgate; Martyn F. Guest; Robert J. Munn; Trudy Workman; Thomas R. Connor; William Fuller; Catherine Bresner; Luke B. Snell; Themoula Charalampous; Gaia Nebbia; Rahul Batra; Jonathan Edgeworth; Samuel C. Robson; Angela H. Beckett; Katie F. Loveson; David M. Aanensen; Anthony P. Underwood; Corin Yeats; Khalil Abudahab; Ben Taylor; Mirko Menegazzo; Gemma Clark; Darren Smith; Manjinder Khakh; Vicki M. Fleming; Michelle M. Lister; Hannah C. Howson‐Wells; Louise Berry; Tim Boswell; Amelia Joseph; Iona Willingham; Paul W. Bird; Thomas Helmer; Karlie Fallon; Christopher W. Holmes; Julian W. Tang; Veena Raviprakash; Stephen Campbell

doi:10.1016/j.cell.2020.11.020

Keywords

BiologyTransmissibility (structural dynamics)Spike (software development)GeneticsMutationNegative selectionGenomeGenetic variationPopulationSelection (genetic algorithm)GeneDemography

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Publication Info

Year: 2020
Type: article
Volume: 184
Issue: 1
Pages: 64-75.e11
Citations: 1054
Access: Closed

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APA Style

                            
                                
                                    Erik Volz, 
                                
                                    Verity Hill, 
                                
                                    John T. McCrone
                                
                                et al.
                            
                            (2020). 
                            Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity. 
                            Cell
                            , 184
                            (1)
                            , 64-75.e11.
                            https://doi.org/10.1016/j.cell.2020.11.020
                        

Identifiers

DOI: 10.1016/j.cell.2020.11.020