Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding

Abstract

Genital HIV-1 shedding decreased rapidly after ART initiation, consistent with a rapid decrease in infectivity. However, incomplete viral suppression in half of these women may indicate an ongoing risk of transmission.

Keywords

Viral loadInfectivityViral sheddingSex organVirologyMedicineVirusInternal medicineImmunologyBiology

MeSH Terms

AdultAnti-HIV AgentsAntiretroviral TherapyHighly ActiveCervix UteriDNAViralFemaleFollow-Up StudiesHIV InfectionsHIV-1HumansProspective StudiesProvirusesRNAViralSex WorkTreatment OutcomeVagina

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Publication Info

Year: 2007
Type: article
Volume: 21
Issue: 4
Pages: 501-507
Citations: 135
Access: Closed

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APA Style

                            
                                
                                    Susan M. Graham, 
                                
                                    Sarah Holte, 
                                
                                    Norbert Peshu
                                
                                et al.
                            
                            (2007). 
                            Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding. 
                            AIDS
                            , 21
                            (4)
                            , 501-507.
                            https://doi.org/10.1097/qad.0b013e32801424bd
                        

Identifiers

DOI: 10.1097/qad.0b013e32801424bd
PMID: 17301569

Data Quality

Data completeness: 90%