Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

Tathiane M. Malta , Artem Sokolov , Andrew J. Gentles , Tathiane M. Malta , Artem Sokolov , Andrew J. Gentles , Tomasz Burzykowski , Laila Poisson , John N. Weinstein , Bożena Kamińska , Joerg Huelsken , Larsson Omberg , Olivier Gevaert , Antonio Colaprico , Patrycja Czerwińska , Sylwia Mazurek , Lopa Mishra , Holger Heyn , A. Krasnitz , Andrew K. Godwin , Alexander J. Lazar , Joshua M. Stuart , Katherine A. Hoadley , Peter W. Laird , Houtan Noushmehr , Maciej Wiznerowicz , Rory Johnson , John A. Demchok , Ina Felau , Melpomeni Kasapi , Martin L. Ferguson , Carolyn M. Hutter , Heidi J. Sofia , Roy Tarnuzzer , Zhining Wang , Liming Yang , Jean C. Zenklusen , Jiashan Zhang , Sudha Chudamani , Jia Liu , Laxmi Lolla , Rashi Naresh , Todd Pihl , Qiang Sun , Yunhu Wan , Ye Wu , Juok Cho , Timothy Defreitas , Scott Frazer , Nils Gehlenborg , Gad Getz , David I. Heiman , Jaegil Kim , Michael S. Lawrence , Pei Lin , Thomas J. Giordano , Michael S. Noble , Gordon Saksena , Doug Voet , Hailei Zhang , Brady Bernard , Nyasha Chambwe , Varsha Dhankani , Theo Knijnenburg , Roger Kramer , Kalle Leinonen , Yuexin Liu , Michael B. Miller , Sheila M. Reynolds , Ilya Shmulevich , Vésteinn Thórsson , Wei Zhang , Rehan Akbani , Bradley M. Broom , Apurva M. Hegde , Zhenlin Ju , Rupa S. Kanchi , Anil Korkut , Jun Li , Han Liang , Shiyun Ling , Wenbin Liu , Yiling Lu , Gordon B. Mills , Kwok-Shing Ng , Arvind Rao , Michael T. Ryan , Jing Wang , John N. Weinstein , Jiexin Zhang , Adam Abeshouse , Joshua Armenia , Debyani Chakravarty , Walid K. Chatila , Ino de Bruijn , Galen F. Gao , Benjamin Groß , Zachary Heins , Ritika Kundra , Konnor La , Marc Ladanyi , Augustin Luna , Moriah G. Nissan
2018 Cell 2,223 citations

Keywords

BiologyPhenotypeTumor microenvironmentInduced pluripotent stem cellEpigeneticsCancer stem cellTranscriptomeProgenitor cellCancer researchStem cellCancerComputational biologyGeneticsEmbryonic stem cellGeneGene expression

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Year
2018
Type
article
Volume
173
Issue
2
Pages
338-354.e15
Citations
2223
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Closed

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Tathiane M. Malta, Artem Sokolov, Andrew J. Gentles et al. (2018). Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell , 173 (2) , 338-354.e15. https://doi.org/10.1016/j.cell.2018.03.034

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DOI
10.1016/j.cell.2018.03.034