New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

Zhenyu Zhong; Shuang Liang; Elsa Sánchez‐López; Feng He; Shabnam Shalapour; Xue-Jia Lin; Jerry Wong; Siyuan Ding; Ekihiro Seki; Bernd Schnabl; Andrea L. Hevener; Harry B. Greenberg; Tatiana Kisseleva; Michael Karin

doi:10.1038/s41586-018-0372-z

Keywords

InflammasomeTRIFMitochondrial DNACell biologyChemistryAIM2MitochondrionCytosolReceptorInnate immune systemBiologyGeneBiochemistryEnzymeToll-like receptor

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Publication Info

Year: 2018
Type: article
Volume: 560
Issue: 7717
Pages: 198-203
Citations: 1068
Access: Closed

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APA Style

                            
                                
                                    Zhenyu Zhong, 
                                
                                    Shuang Liang, 
                                
                                    Elsa Sánchez‐López
                                
                                et al.
                            
                            (2018). 
                            New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. 
                            Nature
                            , 560
                            (7717)
                            , 198-203.
                            https://doi.org/10.1038/s41586-018-0372-z
                        

Identifiers

DOI: 10.1038/s41586-018-0372-z