Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard; Catherine Cannon; Robin Barbour; Rae-Lyn Burke; Dora Games; Henry Grajeda; Teresa Guido; Kang Hu; Jiping Huang; Kelly Johnson‐Wood; Karen Khan; Dora Kholodenko; Mike Lee; Ivan Lieberburg; Ruth Motter; Minh Dang Nguyen; Ferdie Soriano; Nicki Vasquez; Kim Altman Weiss; Brent Welch; Peter Seubert; Dale Schenk; Ted Yednock

doi:10.1038/78682

Keywords

Senile plaquesAmyloid (mycology)P3 peptideAntibodyAmyloid precursor proteinAlzheimer's diseaseGenetically modified mouseMedicineBACE1-ASCentral nervous systemImmunologyPathologyBiologyTransgeneDiseaseEndocrinologyBiochemistry

Affiliated Institutions

Sunesis (United States) US

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Publication Info

Year: 2000
Type: article
Volume: 6
Issue: 8
Pages: 916-919
Citations: 1970
Access: Closed

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APA Style

                            
                                
                                    Frédérique Bard, 
                                
                                    Catherine Cannon, 
                                
                                    Robin Barbour
                                
                                et al.
                            
                            (2000). 
                            Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. 
                            Nature Medicine
                            , 6
                            (8)
                            , 916-919.
                            https://doi.org/10.1038/78682
                        

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DOI: 10.1038/78682