Abstract
The MBE relaxes the instrumental variable assumptions, and should be used in combination with other approaches in sensitivity analyses.
Keywords
Mendelian randomizationInstrumental variablePleiotropyCausal inferenceGenome-wide association studySample size determinationStatisticsInferenceGenetic associationEconometricsComputer scienceMedicineMathematicsSingle-nucleotide polymorphismBiologyGeneticsArtificial intelligenceGenetic variants
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Publication Info
- Year
- 2017
- Type
- article
- Volume
- 46
- Issue
- 6
- Pages
- 1985-1998
- Citations
- 3382
- Access
- Closed
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Cite This
Fernando Pires Hartwig,
George Davey Smith,
Jack Bowden
(2017).
Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption.
International Journal of Epidemiology
, 46
(6)
, 1985-1998.
https://doi.org/10.1093/ije/dyx102
Identifiers
- DOI
- 10.1093/ije/dyx102