Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

Shira Cramer; Achinto Saha; Jinyun Liu; Surendar Tadi; Stefano Tiziani; Wupeng Yan; Kendra Triplett; Candice Lamb; Susan E. Alters; Scott W. Rowlinson; Yan Zhang; Michael J. Keating; Peng Huang; John DiGiovanni; George Georgiou; Everett Stone

doi:10.1038/nm.4232

Keywords

Reactive oxygen speciesGlutathioneOxidative stressCancer researchCancer cellIntracellularExtracellularBiologyAntioxidantCancerChemistryBiochemistryInternal medicineEnzymeMedicine

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Publication Info

Year: 2016
Type: article
Volume: 23
Issue: 1
Pages: 120-127
Citations: 509
Access: Closed

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APA Style

                            
                                
                                    Shira Cramer, 
                                
                                    Achinto Saha, 
                                
                                    Jinyun Liu
                                
                                et al.
                            
                            (2016). 
                            Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. 
                            Nature Medicine
                            , 23
                            (1)
                            , 120-127.
                            https://doi.org/10.1038/nm.4232
                        

Identifiers

DOI: 10.1038/nm.4232