Abstract
Publication bias is the tendency on the parts of investigators, reviewers, and editors to submit or accept manuscripts for publication based on the direction or strength of the study findings. Much of what has been learned about publication bias comes from the social sciences, less from the field of medicine. In medicine, three studies have provided direct evidence for this bias. Prevention of publication bias is important both from the scientific perspective (complete dissemination of knowledge) and from the perspective of those who combine results from a number of similar studies (meta-analysis). If treatment decisions are based on the published literature, then the literature must include all available data that is of acceptable quality. Currently, obtaining information regarding all studies undertaken in a given field is difficult, even impossible. Registration of clinical trials, and perhaps other types of studies, is the direction in which the scientific community should move.
Keywords
Affiliated Institutions
Related Publications
Modelling multiple sources of dissemination bias in meta‐analysis
Abstract Asymmetry in the funnel plot for a meta‐analysis suggests the presence of dissemination bias. This may be caused by publication bias through the decisions of journal ed...
Raising the bar for systematic reviews with Assessment of Multiple Systematic Reviews ( <scp>AMSTAR</scp> )
The BJUI has a longstanding track record in promoting the dissemination of high-quality unbiased evidence and helping their readership to understand why the principles of eviden...
Publication Bias: A Problem in Interpreting Medical Data
Publication bias, the phenomenon in which studies with positive results are more likely to be published than studies with negative results, is a serious problem in the interpret...
Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy
The consolidation of scientific knowledge proceeds through the interpretation and then distillation of data presented in research reports, first in review articles and then in t...
Meta-Analyses in Orthopaedic Surgery
The majority of meta-analyses on orthopaedic-surgery-related topics have methodological limitations. Limitation of bias and improvement in the validity of the meta-analyses can ...
Publication Info
- Year
- 1990
- Type
- article
- Volume
- 263
- Issue
- 10
- Pages
- 1385-1385
- Citations
- 1343
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1001/jama.1990.03440100097014