Keywords
Affiliated Institutions
Related Publications
TGF-β SIGNAL TRANSDUCTION
The transforming growth factor β (TGF-β) family of growth factors control the development and homeostasis of most tissues in metazoan organisms. Work over the past few years has...
Peptide growth factors in the intestine
A continuously increasing number of regulatory peptides has been demonstrated to be expressed in the intestine and to modulate several functional properties of various intestina...
Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction
The mitogen-activated protein kinase (MAPK) pathway is a conserved eukaryotic signaling module that converts receptor signals into various outputs. MAPK is activated through pho...
Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.
A panel of 71 chemically mutagenized Mv1Lu mink lung epithelial cell clones were selected based on their resistance to the growth inhibitory action of transforming growth factor...
Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta.
Transforming growth factor-beta (TGF-beta) transduces signals through a heteromeric complex of type I (T beta R-I) and type II (T beta R-II) TGF-beta receptors. To determine the...
Publication Info
- Year
- 1990
- Type
- review
- Volume
- 6
- Issue
- 1
- Pages
- 597-641
- Citations
- 3019
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1146/annurev.cb.06.110190.003121