Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer

2005 New England Journal of Medicine 5,034 citations

Abstract

One year of treatment with trastuzumab after adjuvant chemotherapy significantly improves disease-free survival among women with HER2-positive breast cancer. (ClinicalTrials.gov number, NCT00045032.)

Keywords

TrastuzumabMedicineBreast cancerOncologyChemotherapyAdjuvantMonoclonal antibodyInternal medicineAdjuvant chemotherapyCancerStage (stratigraphy)AntibodyImmunology

Affiliated Institutions

Related Publications

Trastuzumab and Vinorelbine as First-Line Therapy for HER2-Overexpressing Metastatic Breast Cancer: Multicenter Phase II Trial With Clinical Outcomes, Analysis of Serum Tumor Markers as Predictive Factors, and Cardiac Surveillance Algorithm

Purpose: Trastuzumab-based therapy improves survival for women with human epidermal growth factor receptor 2 (HER2)–positive advanced breast cancer. We conducted a multicenter p...

2003 Journal of Clinical Oncology 343 citations

Publication Info

Year
2005
Type
article
Volume
353
Issue
16
Pages
1659-1672
Citations
5034
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

5034
OpenAlex

Cite This

Martine Piccart, Marion Procter, Brian Leyland‐Jones et al. (2005). Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer. New England Journal of Medicine , 353 (16) , 1659-1672. https://doi.org/10.1056/nejmoa052306

Identifiers

DOI
10.1056/nejmoa052306