Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin

Elizabeth Ziegler; Charles J. Fisher; Charles L. Sprung; Richard Straube; Jerald Sadoff; Garrett E. Foulke; Cornelis H. Wortel; Mitchell P. Fink; R. Phillip Dellinger; Nelson N.H. Teng; I. Elaine Allen; Harvey J. Berger; Genell L. Knatterud; Albert F. LoBuglio; Craig R. Smith

doi:10.1056/nejm199102143240701

Abstract

HA-1A is safe and effective for the treatment of patients with sepsis and gram-negative bacteremia.

Keywords

BacteremiaMedicineSepsisSeptic shockPlaceboInternal medicineRandomized controlled trialAntibioticsShock (circulatory)GastroenterologyImmunologySurgeryPathologyMicrobiology

MeSH Terms

AntibodiesMonoclonalDouble-Blind MethodEndotoxinsFemaleGram-Negative BacteriaHumansMaleMiddle AgedProspective StudiesSepsisShockSeptic

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Publication Info

Year: 1991
Type: article
Volume: 324
Issue: 7
Pages: 429-436
Citations: 1619
Access: Closed

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APA Style

                            
                                
                                    Elizabeth Ziegler, 
                                
                                    Charles J. Fisher, 
                                
                                    Charles L. Sprung
                                
                                et al.
                            
                            (1991). 
                            Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin. 
                            New England Journal of Medicine
                            , 324
                            (7)
                            , 429-436.
                            https://doi.org/10.1056/nejm199102143240701
                        

Identifiers

DOI: 10.1056/nejm199102143240701
PMID: 1988827

Data Quality

Data completeness: 86%