Publications
Explore 115 academic publications
The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice
A translational medicine pipeline is described where human gut microbial communities and diets are re-created in gnotobiotic mice and the impact on microbe and host is defined u...
Purification and Characterization of Mouse Hematopoietic Stem Cells
Mouse bone marrow hematopoietic stem cells were isolated with the use of a variety of phenotypic markers. These cells can proliferate and differentiate with approximately unit e...
Wnt signaling: a common theme in animal development
Wnt proteins are now recognized as one of the major families of developmentally important signaling molecules, with mutations in Wnt genes displaying remarkable phenotypes in th...
Habitat, the Templet for Ecological Strategies?
The very etymology of Ecology, from the greek 'Qikos', 'the household', implies that ecologists should devote some attention to the 'house' or habitat of the population or commu...
Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell
Hematopoietic stem cells (HSCs) supply all blood cells throughout life by making use of their self-renewal and multilineage differentiation capabilities. A monoclonal antibody r...
TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
Somatic mutations in the TP53 gene are one of the most frequent alterations in human cancers, and germline mutations are the underlying cause of Li-Fraumeni syndrome, which pred...
Matching People and Organizations: Selection and Socialization in Public Accounting Firms
Understanding and predicting behavior in organizations requires a consideration of person and situation factors, and how these factors interact. This paper develops and longitud...