An Integrated Genomic Analysis of Human Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer. To identify the genetic alterations in GBMs, we sequenced 20,661 protein coding genes, determin...
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2,734 publications
Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection
In patients with ischemic stroke with a proximal cerebral arterial occlusion and salvageable tissue on CT perfusion imaging, early thrombectomy with the Solitaire FR stent retri...
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stro...
ILAE Official Report: A practical clinical definition of epilepsy
Summary Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. This definition is usual...
Oxygen-Derived Free Radicals in Postischemic Tissue Injury
It is now clear that oxygen-derived free radicals play an important part in several models of experimentally induced reperfusion injury. Although there are certainly multiple co...
Heart Disease and Stroke Statistics—2021 Update
Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stro...
Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System
Neurogenesis in the mammalian central nervous system is believed to end in the period just after birth; in the mouse striatum no new neurons are produced after the first few day...
Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels
Pravastatin therapy reduced mortality from coronary heart disease and overall mortality, as compared with the rates in the placebo group, as well as the incidence of all prespec...
A Short Portable Mental Status Questionnaire for the Assessment of Organic Brain Deficit in Elderly Patients†
ABSTRACT Clinicians whose practice includes elderly patients need a short, reliable instrument to detect the presence of intellectual impairment and to determine the degree. A 1...