Publications

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data. GEO provides a flexib...

A method and server for predicting damaging missense mutations

Twelve years of SAMtools and BCFtools

Abstract Background SAMtools and BCFtools are widely used programs for processing and analysing high-throughput sequencing data. They include tools for file format conversion an...

RNA-Seq: a revolutionary tool for transcriptomics

A new coronavirus associated with human respiratory disease in China

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

lin-4 is essential for the normal temporal control of diverse postembryonic developmental events in C. elegans. lin-4 acts by negatively regulating the level of LIN-14 protein, ...

SWISS-MODEL: homology modelling of protein structures and complexes

Homology modelling has matured into an important technique in structural biology, significantly contributing to narrowing the gap between known protein sequences and experimenta...

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

Bioconductor: open software development for computational biology and bioinformatics

An obesity-associated gut microbiome with increased capacity for energy harvest

Comprehensive molecular portraits of human breast tumours