David B. Jaffe

Assemblathon 1: A competitive assessment of de novo short read assembly methods

Low-cost short read sequencing technology has revolutionized genomics, though it is only just becoming practical for the high-quality de novo assembly of a novel large genome. W...

ALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads

Initial sequencing and comparative analysis of the mouse genome

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Demographic history and rare allele sharing among human populations

High-throughput sequencing technology enables population-level surveys of human genomic variation. Here, we examine the joint allele frequency distributions across continental h...

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

Finished bacterial genomes from shotgun sequence data

Exceptionally accurate genome reference sequences have proven to be of great value to microbial researchers. Thus, to date, about 1800 bacterial genome assemblies have been “fin...