Marcel P. Bruchez

Semiconductor Nanocrystals as Fluorescent Biological Labels

Semiconductor nanocrystals were prepared for use as fluorescent probes in biological staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have a n...

Organization of 'nanocrystal molecules' using DNA

Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots

Semiconductor quantum dots (QDs) are among the most promising emerging fluorescent labels for cellular imaging. However, it is unclear whether QDs, which are nanoparticles rathe...

Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo

The use of semiconductor nanocrystals (quantum dots) as fluorescent labels for multiphoton microscopy enables multicolor imaging in demanding biological environments such as liv...

Properties of Fluorescent Semiconductor Nanocrystals and their Application to Biological Labeling

We review recent advances in the development of colloidal fluorescent semiconductor nanocrystals (a class of quantum dots) for biological labeling. Although some of the photophy...

Noninvasive Imaging of Quantum Dots in Mice

Quantum dots having four different surface coatings were tested for use in in vivo imaging. Localization was successfully monitored by fluorescence imaging of living animals, by...