Stuart L. Schreiber

A mammalian protein targeted by G1-arresting rapamycin–receptor complex

Control of p70 S6 kinase by kinase activity of FRAP in vivo

An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

A Planning Strategy for Diversity‐Oriented Synthesis

Abstract In contrast to target‐oriented synthesis (TOS) and medicinal or combinatorial chemistry, which aim to access precise or dense regions of chemistry space, diversity‐orie...

Regulation of Ferroptotic Cancer Cell Death by GPX4

Methylation of histone H3 Lys 4 in coding regions of active genes

Posttranslational modifications of histone tails regulate chromatin structure and transcription. Here we present global analyses of histone acetylation and histone H3 Lys 4 meth...

Single-Nucleosome Mapping of Histone Modifications in S. cerevisiae

Covalent modification of histone proteins plays a role in virtually every process on eukaryotic DNA, from transcription to DNA repair. Many different residues can be covalently ...