Guy's Hospital

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We descri...

Structure-antioxidant activity relationships of flavonoids and phenolic acids

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

A framework for advancing our understanding of cancer-associated fibroblasts

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

The landscape of cancer genes and mutational processes in breast cancer

All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer clonal selective advantage on cancer cells and are causally implicated in oncog...

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Copy number variants (CNVs) account for a major proportion of human genetic polymorphism and have been predicted to have an important role in genetic susceptibility to common di...

Assessment of response to therapy in advanced breast cancer.A project of the programme on clinical oncology of the International Union against Cancer, Geneva, Switzerland

SCOPUS: ar.j

Bayesian refinement of association signals for 14 loci in 3 common diseases

Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs