Announcing mandatory submission of PDBx/mmCIF format files for crystallographic depositions to the Protein Data Bank (PDB)

Abstract

The Protein Data Bank (PDB) (wwPDB consortium, 2019) is the single global archive of experimentally determined three-dimensional (3D) structure data of biological macromolecules. The continuing growth in the numbers, size and complexity of macromolecular structures in the PDB archive, coupled with the rapid growth of evolving experimental methods such as 3D cryo-electron microscopy (3DEM) has made the traditional PDB format (`legacy PDB format') inadequate for fully representing these data. Here, as described below, this format was based on a punched-card format that became obsolete long ago. In the following letter, we describe the changes necessary to address the challenges coming from the extraordinary success of structural biologists.

Keywords

Affiliated Institutions

• University of California, Berkeley US
• University of Wisconsin–Madison US
• European Bioinformatics Institute GB
• Lawrence Berkeley National Laboratory US
• UConn Health US
• Global Phasing (United Kingdom) GB
• Newcastle University GB
• Rutherford Appleton Laboratory GB
• University of California, San Diego US
• Protein Research Foundation JP
• Research Complex at Harwell GB
• MRC Laboratory of Molecular Biology GB
• Rutgers, The State University of New Jersey US
• San Diego Supercomputer Center US
• University of Kent GB
• Rutgers Cancer Institute
• The University of Osaka JP

Related Publications