Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Abstract

Cervical cancer is a malignant epithelial tumor that forms in the uterine cervix. Most cases of cervical cancer are preventable through human papilloma virus (HPV) vaccination, routine screening, and treatment of precancerous lesions. However, due to inadequate screening protocols in many regions of the world, cervical cancer remains the fourth-most common cancer in women globally. The complete NCCN Guidelines for Cervical Cancer provide recommendations for the diagnosis, evaluation, and treatment of cervical cancer. This manuscript discusses guiding principles for the workup, staging, and treatment of early stage and locally advanced cervical cancer, as well as evidence for these recommendations. For recommendations regarding treatment of recurrent or metastatic disease, please see the full guidelines on NCCN.org.

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Affiliated Institutions

• UCSF Helen Diller Family Comprehensive Cancer Center US
• University of Utah US
• University of Tennessee Health Science Center US
• UC San Diego Health System US
• Huntsman Cancer Institute US
• City Of Hope National Medical Center US
• Yale Cancer Center US
• University of Alabama at Birmingham US
• Duke Cancer Institute
• Dana-Farber Brigham Cancer Center US
• Sidney Kimmel Comprehensive Cancer Center US
• Stanford Cancer Institute
• The University of Texas MD Anderson Cancer Center US
• Barnes-Jewish Hospital US
• St. Jude Children's Research Hospital US
• Seattle Cancer Care Alliance US
• Cancer Research Center US
• Fred and Pamela Buffett Cancer Center
• Vanderbilt-Ingram Cancer Center
• Smilow Cancer Hospital US
• Cleveland Clinic US
• Massachusetts General Hospital US
• The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute US
• University of Colorado Cancer Center US
• Fred Hutch Cancer Center US
• Moores Cancer Center
• Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa ZA
• University of Michigan US
• Moffitt Cancer Center US
• University of Colorado Denver US
• University Hospitals Seidman Cancer Center US
• Fox Chase Cancer Center US
• University of Wisconsin Carbone Cancer Center US
• Cancer Institute (WIA) IN
• Jewish Hospital US
• Memorial Sloan Kettering Cancer Center US
• WinnMed US
• National Comprehensive Cancer Network

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