cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading

Abstract

Abstract cIMPACT‐NOW (the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy) was established to evaluate and make practical recommendations on recent advances in the field of CNS tumor classification, particularly in light of the rapid progress in molecular insights into these neoplasms. For Round 2 of its deliberations, cIMPACT‐NOW Working Committee 3 was reconstituted and convened in Utrecht, The Netherlands, for a meeting designed to review putative new CNS tumor types in advance of any future World Health Organization meeting on CNS tumor classification. In preparatory activities for the meeting and at the actual meeting, a list of possible entities was assembled and each type and subtype debated. Working Committee 3 recommended that a substantial number of newly recognized types and subtypes should be considered for inclusion in future CNS tumor classifications. In addition, the group endorsed a number of principles—relating to classification categories, approaches to classification, nomenclature, and grading—that the group hopes will also inform the future classification of CNS neoplasms.

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Affiliated Institutions

• Harvard University US
• Mayo Clinic US
• Seoul National University KR
• Johns Hopkins Medicine US
• Hopp Children's Cancer Center Heidelberg DE
• University of Zurich CH
• University Hospital Münster DE
• Centre international de recherche sur le cancer FR
• National Cancer Institute US
• Erasmus MC Cancer Institute NL
• University of Toronto CA
• University of Bonn DE
• Amsterdam University Medical Centers NL
• Charité - Universitätsmedizin Berlin DE
• Life & Brain (Germany) DE
• The University of Texas MD Anderson Cancer Center US
• Tokyo Metropolitan Neurological Hospital JP
• SickKids Foundation CA
• St. Jude Children's Research Hospital US
• Erasmus MC NL
• Hospital for Sick Children CA
• All India Institute of Medical Sciences IN
• Freie Universität Berlin DE
• Massachusetts General Hospital US
• Centre National de la Recherche Scientifique FR
• Heinrich Heine University Düsseldorf DE
• German Cancer Research Center DE
• University of Bologna IT
• Northwestern University US
• Deutschen Konsortium für Translationale Krebsforschung
• Humboldt-Universität zu Berlin DE
• University of Cincinnati US
• Medical University of Vienna AT
• Cambridge University Hospitals NHS Foundation Trust GB
• Princess Máxima Center NL
• University Hospital of Zurich CH
• Cincinnati Children's Hospital Medical Center US
• Chinese University of Hong Kong HK
• National Center for Tumor Diseases DE
• Hôpital de la Timone FR
• Johns Hopkins University US
• University of California, San Francisco US
• Institut de Neurophysiopathologie FR
• Memorial Sloan Kettering Cancer Center US
• Heidelberg University DE

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