Genetic analyses of diverse populations improves discovery for complex traits

Sarah C. Nelson , Sung-Shim L. Park , Hannah Poisner , Sarah C. Nelson , Sung-Shim L. Park , Hannah Poisner , Michael Preuß , Melissa A. Richard , Claudia Schurmann , Veronica Wendy Setiawan , Alexandra Sockell , Karan Vahi , Marie Verbanck , Abhishek Vishnu , Ryan W. Walker , Kristin L. Young , Niha Zubair , Victor Acuña-Alonso , José Luis Ambite , Kathleen C. Barnes , Eric Boerwinkle , Erwin P. Böttinger , Carlos D. Bustamante , Christian Caberto , Samuel Canizales‐Quinteros , Matthew P. Conomos , Ewa Deelman , Ron Do , Kimberly F. Doheny , Lindsay Fernández‐Rhodes , Myriam Fornage , Benyam Hailu , Gerardo Heiss , Brenna M. Henn , Lucia A. Hindorff , Rebecca D. Jackson , Cecelia Laurie , Cathy C. Laurie , Yuqing Li , Dan-Yu Lin , Andrés Moreno‐Estrada , Girish N. Nadkarni , Paul J. Norman , Loreall Pooler , Alexander P. Reiner , Jane Romm , Chiara Sabatti , Karla Sandoval , Xin Sheng , Eli A. Stahl , Daniel O. Stram , Timothy A. Thornton , Christina L. Wassel , Lynne R. Wilkens , Cheryl A. Winkler , Sachi Yoneyama , Steven Buyske , Christopher A. Haiman , Charles Kooperberg , Loı̈c Le Marchand , Ruth J. F. Loos , Tara C. Matise , Kari E. North , Ulrike Peters , Eimear E. Kenny , Christopher S. Carlson , Genevieve L. Wojcik , Mariaelisa Graff , Katherine K. Nishimura , Ran Tao , Jeffrey Haessler , Christopher R. Gignoux , Heather M. Highland , Yesha Patel , Elena P. Sorokin , Christy L. Avery , Gillian M. Belbin , Stephanie A. Bien , Iona Cheng , Sinéad Cullina , Chani J. Hodonsky , Yao Hu , Laura M. Huckins , Janina M. Jeff , Anne E. Justice , Jonathan Kocarnik , Unhee Lim , Bridget M. Lin , Yingchang Lu
2019 Nature 1,034 citations

Keywords

Genome-wide association studyGenetic architecturePopulationBiologyGenomicsGenetic associationEvolutionary biologyEthnic groupPopulation genomicsGenetic epidemiologyGeneticsComputational biologyData scienceQuantitative trait locusGenomeMedicineSingle-nucleotide polymorphismGeneComputer scienceGenotype

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Publication Info

Year
2019
Type
article
Volume
570
Issue
7762
Pages
514-518
Citations
1034
Access
Closed

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Sarah C. Nelson, Sung-Shim L. Park, Hannah Poisner et al. (2019). Genetic analyses of diverse populations improves discovery for complex traits. Nature , 570 (7762) , 514-518. https://doi.org/10.1038/s41586-019-1310-4

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DOI
10.1038/s41586-019-1310-4