NCCN Guidelines Insights: Colon Cancer, Version 2.2018

Al B. Benson; Alan P. Venook; Mahmoud M. Al-Hawary; Lynette Cederquist; Yi‐Jen Chen; Kristen K. Ciombor; Stacey A. Cohen; Harry S. Cooper; Dustin A. Deming; Paul F. Engstrom; Ignacio Garrido‐Laguna; Jean L. Grem; Axel Grothey; Howard S. Höchster; Sarah E. Hoffe; Steven R. Hunt; Ahmed Kamel; Natalie Kirilcuk; Smitha Krishnamurthi; Wells A. Messersmith; Jeffrey A. Meyerhardt; Eric D. Miller; Mary F. Mulcahy; James D. Murphy; Steven Nurkin; Leonard B. Saltz; Sunil Sharma; David Shibata; John M. Skibber; Constantinos T. Sofocleous; Elena M. Stoffel; Eden Stotsky‐Himelfarb; Christopher G. Willett; Evan Wuthrick; Kristina M. Gregory; Deborah A. Freedman-Cass

doi:10.6004/jnccn.2018.0021

Abstract

The NCCN Guidelines for Colon Cancer provide recommendations regarding diagnosis, pathologic staging, surgical management, perioperative treatment, surveillance, management of recurrent and metastatic disease, and survivorship. These NCCN Guidelines Insights summarize the NCCN Colon Cancer Panel discussions for the 2018 update of the guidelines regarding risk stratification and adjuvant treatment for patients with stage III colon cancer, and treatment of <i>BRAF</i> V600E mutation-positive metastatic colorectal cancer with regimens containing vemurafenib.

Keywords

MedicineColorectal cancerVemurafenibOncologyInternal medicinePerioperativeRisk stratificationCancerDiseaseGeneral surgeryIntensive care medicineSurgeryMetastatic melanoma

Affiliated Institutions

Related Publications

Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology

Al B. Benson , Alan P. Venook , Mahmoud M. Al-Hawary +36 more

This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Colon Cancer focuses on systemic therapy options for the treatment of metastatic colo...

2021 Journal of the National Comprehensive... 1622 citations

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

Keith T. Flaherty , Igor Puzanov , Kevin B. Kim +8 more

Treatment of metastatic melanoma with PLX4032 in patients with tumors that carry the V600E BRAF mutation resulted in complete or partial tumor regression in the majority of pati...

2010 New England Journal of Medicine 3499 citations

Prostate Cancer, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology

James L. Mohler , Emmanuel S. Antonarakis , Andrew J. Armstrong +30 more

The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis, risk stratification and workup, treatment options for localized disease, and management of r...

2019 Journal of the National Comprehensive... 1534 citations

Encorafenib, Binimetinib, and Cetuximab in <i>BRAF</i> V600E–Mutated Colorectal Cancer

Scott Kopetz , Axel Grothey , Rona Yaeger +32 more

A combination of encorafenib, cetuximab, and binimetinib resulted in significantly longer overall survival and a higher response rate than standard therapy in patients with meta...

2019 New England Journal of Medicine 1353 citations

Advances in the surgical management of pancreatic cancer.

Kathryn Spanknebel , Kevin C. Conlon

Pancreatic cancer continues to pose a major public health concern and clinical challenge. The incidence of the disease is nearly equivalent to the death rate associated with the...

2002 PubMed 92 citations

Publication Info

Year: 2018
Type: article
Volume: 16
Issue: 4
Pages: 359-369
Citations: 979
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

NCCN Guidelines Insights: Colon Cancer, Version 2.2018

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

979

OpenAlex

Cite This

APA Style

                            
                                
                                    Al B. Benson, 
                                
                                    Alan P. Venook, 
                                
                                    Mahmoud M. Al-Hawary
                                
                                et al.
                            
                            (2018). 
                            NCCN Guidelines Insights: Colon Cancer, Version 2.2018. 
                            Journal of the National Comprehensive Cancer Network
                            , 16
                            (4)
                            , 359-369.
                            https://doi.org/10.6004/jnccn.2018.0021
                        

Identifiers

DOI: 10.6004/jnccn.2018.0021