Protein Misfolding, Functional Amyloid, and Human Disease
Peptides or proteins convert under some conditions from their soluble forms into highly ordered fibrillar aggregates. Such transitions can give rise to pathological conditions r...
Publications
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2,333 publications
Crystal Statistics. I. A Two-Dimensional Model with an Order-Disorder Transition
The partition function of a two-dimensional "ferromagnetic" with scalar "spins" (Ising model) is computed rigorously for the case of vanishing field. The eigenwert problem invol...
<i>Planck</i>2013 results. XVI. Cosmological parameters
This paper presents the first cosmological results based on <em>Planck</em> measurements of the cosmic microwave background (CMB) temperature and lensing-potential p...
Comprehensive organic synthesis
The second edition of Comprehensive Organic Synthesis builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate a...
Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer
In patients with previously untreated metastatic nonsquamous NSCLC without EGFR or ALK mutations, the addition of pembrolizumab to standard chemotherapy of pemetrexed and a plat...
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
BACKGROUND In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through ...
Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer
In addition to HPV types 16 and 18, types 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73, and 82 should be considered carcinogenic, or high-risk, types, and types 26, 53, and 66...
The carbohydrate-active enzymes database (CAZy) in 2013
The Carbohydrate-Active Enzymes database (CAZy; http://www.cazy.org) provides online and continuously updated access to a sequence-based family classification linking the sequen...
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.
Several polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per s...
The Effect of Cardiac Resynchronization on Morbidity and Mortality in Heart Failure
In patients with heart failure and cardiac dyssynchrony, cardiac resynchronization improves symptoms and the quality of life and reduces complications and the risk of death. The...
The Econometrics of Financial Markets
This book is an ambitious effort by three well-known and well-respected scholars to fill an acknowledged void in the literature—a text covering the burgeoning field of empirical...
Political Order in Changing Societies
now-classic examination of the development of viable political institutions in emerging nations is a major and enduring contribution to modern political analysis. In a new Forew...