Why Most Published Research Findings Are False
There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number...
Publications
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8,296 publications
Feature selection based on mutual information criteria of max-dependency, max-relevance, and min-redundancy
Feature selection is an important problem for pattern classification systems. We study how to select good features according to the maximal statistical dependency criterion base...
Tumor Angiogenesis: Therapeutic Implications
THE growth of solid neoplasms is always accompanied by neovascularization. This new capillary growth is even more vigorous and continuous than a similar outgrowth of capillary s...
VSEARCH: a versatile open source tool for metagenomics
Background VSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence...
The basics of epithelial-mesenchymal transition
The origins of the mesenchymal cells participating in tissue repair and pathological processes, notably tissue fibrosis, tumor invasiveness, and metastasis, are poorly understoo...
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
An adaption of Egger regression (which we call MR-Egger) can detect some violations of the standard instrumental variable assumptions, and provide an effect estimate which is no...
Complex heatmaps reveal patterns and correlations in multidimensional genomic data
Abstract Summary: Parallel heatmaps with carefully designed annotation graphics are powerful for efficient visualization of patterns and relationships among high dimensional gen...
Statistical significance for genomewide studies
With the increase in genomewide experiments and the sequencing of multiple genomes, the analysis of large data sets has become commonplace in biology. It is often the case that ...