Publications
12 shownUnderstanding the tumor immune microenvironment (TIME) for effective therapy
The clinical successes in immunotherapy have been both astounding and at the same time unsatisfactory. Countless patients with varied tumor types have seen pronounced clinical r...
The basics of epithelial-mesenchymal transition
The origins of the mesenchymal cells participating in tissue repair and pathological processes, notably tissue fibrosis, tumor invasiveness, and metastasis, are poorly understoo...
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
A number of genetic mutations have been identified in human breast cancers, yet the specific combinations of mutations required in concert to form breast carcinoma cells remain ...
Mesenchyme Forkhead 1 ( <i>FOXC2</i> ) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
The metastatic spread of epithelial cancer cells from the primary tumor to distant organs mimics the cell migrations that occur during embryogenesis. Using gene expression profi...
The Spemann organizer gene, <i>Goosecoid</i> , promotes tumor metastasis
The process of invasion and metastasis during tumor progression is often reminiscent of cell migration events occurring during embryonic development. We hypothesized that genes ...
Frequent Co-Authors
Researcher Info
- h-index
- 12
- Publications
- 12
- Citations
- 125,780
- Institution
- Whitehead Institute for Biomedical Research
External Links
Identifiers
- ORCID
- 0000-0002-0895-3557
Impact Metrics
h-index: Number of publications with at least h citations each.