Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

Katherine A. Hoadley , Christina Yau , Toshinori Hinoue , Katherine A. Hoadley , Christina Yau , Toshinori Hinoue , Denise M. Wolf , Alexander J. Lazar , Esther Drill , Ronglai Shen , Alison M. Taylor , Andrew D. Cherniack , Vésteinn Thórsson , Rehan Akbani , Reanne Bowlby , Christopher K. Wong , Maciej Wiznerowicz , Francisco Sánchez-Vega , Lewis R. Roberts , Barbara Schneider , Michael S. Lawrence , Houtan Noushmehr , Tathiane M. Malta , Joshua M. Stuart , Christopher C. Benz , Peter W. Laird , Rory Johnson , John A. Demchok , Ina Felau , Melpomeni Kasapi , Martin L. Ferguson , Carolyn M. Hutter , Heidi J. Sofia , Roy Tarnuzzer , Linghua Wang , Liming Yang , Jean C. Zenklusen , Jiashan Zhang , Sudha Chudamani , Jia Liu , Laxmi Lolla , Rashi Naresh , Todd Pihl , Qiang Sun , Yunhu Wan , Ye Wu , Juok Cho , Timothy Defreitas , Scott Frazer , Nils Gehlenborg , Gad Getz , David I. Heiman , Seungchan Kim , Michael S. Lawrence , Pei Lin , Thomas J. Giordano , Michael S. Noble , Gordon Saksena , Doug Voet , Hailei Zhang , Brady Bernard , Nyasha Chambwe , Varsha Dhankani , Theo Knijnenburg , Roger Kramer , Kalle Leinonen , Yuexin Liu , Michael Miller , Sheila M. Reynolds , Ilya Shmulevich , Vésteinn Thórsson , Wei Zhang , Rehan Akbani , Bradley M. Broom , Apurva M. Hegde , Zhenlin Ju , Rupa S. Kanchi , Anil Korkut , Jun Li , Han Liang , Shiyun Ling , Wenbin Liu , Yiling Lu , Gordon B. Mills , Kwok-Shing Ng , Arvind Rao , Michael P. Ryan , Jing Wang , John N. Weinstein , Jiexin Zhang , Adam Abeshouse , Joshua Armenia , Debyani Chakravarty , Walid K. Chatila , Ino de Bruijn , Galen F. Gao , Benjamin Groß , Zachary Heins , Ritika Kundra , Konnor La , Marc Ladanyi , Augustin Luna , Moriah G. Nissan
2018 Cell 2,477 citations

Keywords

BiologyDNA methylationCancerAneuploidyMethylationCell typeCancer researchGeneticsComputational biologyDNACellGeneChromosomeGene expression

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Year
2018
Type
article
Volume
173
Issue
2
Pages
291-304.e6
Citations
2477
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Katherine A. Hoadley, Christina Yau, Toshinori Hinoue et al. (2018). Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell , 173 (2) , 291-304.e6. https://doi.org/10.1016/j.cell.2018.03.022

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DOI
10.1016/j.cell.2018.03.022