The repertoire of mutational signatures in human cancer

Ludmil B. Alexandrov , Jaegil Kim , Nicholas J. Haradhvala , Ludmil B. Alexandrov , Jaegil Kim , Nicholas J. Haradhvala , Mi Ni Huang , Alvin Wei Tian Ng , Yang Wu , Arnoud Boot , Kyle R. Covington , Dmitry A. Gordenin , Erik N. Bergstrom , S. M. Ashiqul Islam , Núria López-Bigas , Leszek J. Klimczak , John R. McPherson , Sandro Morganella , Radhakrishnan Sabarinathan , David A. Wheeler , Ville Mustonen , Ludmil B. Alexandrov , Erik N. Bergstrom , Arnoud Boot , Paul C. Boutros , Kin Chan , Kyle R. Covington , Akihiro Fujimoto , Gad Getz , Dmitry A. Gordenin , Nicholas J. Haradhvala , Mi Ni Huang , S. M. Ashiqul Islam , Marat D. Kazanov , Jaegil Kim , Leszek J. Klimczak , Núria López-Bigas , Michael S. Lawrence , Iñigo Martincorena , John R. McPherson , Sandro Morganella , Ville Mustonen , Hidewaki Nakagawa , Alvin Wei Tian Ng , Paz Polak , Stephenie D. Prokopec , Steven A. Roberts , Steve Rozen , Radhakrishnan Sabarinathan , Natalie Saini , Tatsuhiro Shibata , Yuichi Shiraishi , Michael R. Stratton , Bin Tean Teh , Ignacio Vázquez-Garćıa , David A. Wheeler , Yang Wu , Fouad Yousif , Willie Yu , Gad Getz , Steve Rozen , Michael R. Stratton , Lauri A. Aaltonen , Federico Abascal , Adam Abeshouse , Hiroyuki Aburatani , David J. Adams , Nishant Agrawal , Keun Soo Ahn , Sung‐Min Ahn , Hiroshi Aikata , Rehan Akbani , Kadir C. Akdemir , Hikmat Al‐Ahmadie , Sultan T. Al‐Sedairy , Fátima Al‐Shahrour , Malik Alawi , Monique Albert , Kenneth Aldape , Ludmil B. Alexandrov , Adrian Ally , Kathryn Alsop , Eva G. Álvarez , Fernanda Amary , Samirkumar B. Amin , Brice Aminou , Ole Ammerpohl , Matthew J. Anderson , Yeng Ang , Davide Antonello , Pavana Anur , Samuel Aparício , Elizabeth L. Appelbaum , Yasuhito Arai , Axel Aretz , Koji Arihiro , Shun‐ichi Ariizumi , Joshua Armenia , Laurent Arnould , L. Sylvia , Yassen Assenov , Gurnit Atwal , Sietse Aukema
2020 Nature 3,401 citations

Keywords

Somatic cellGeneticsBiologyGenomeCancerRepertoireMutationComputational biologyHuman genomeEvolutionary biologyGene

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Year
2020
Type
article
Volume
578
Issue
7793
Pages
94-101
Citations
3401
Access
Closed

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Ludmil B. Alexandrov, Jaegil Kim, Nicholas J. Haradhvala et al. (2020). The repertoire of mutational signatures in human cancer. Nature , 578 (7793) , 94-101. https://doi.org/10.1038/s41586-020-1943-3

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DOI
10.1038/s41586-020-1943-3